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For Overweight/Obese Patients: Individuals prescribed Wegovy for weight management saw an even more dramatic spike, measuring 7 times more likely to develop NAION than those using alternative weight-loss treatments

The most common criticism against GLP-1 users is that they're taking the "easy way out." This comes from a basic misunderstanding of obesity as a chronic disease, not a lack of discipline.10 It's crucial to remember that GLP-1s are medical treatments for a complex condition, similar to bariatric surgery, designed to address underlying biological mechanisms that make weight loss incredibly hard for many.10 The data clearly shows how common and where this shaming comes from 13 : Half of all people taking GLP-1 medication report experiencing judgment or shame

Treatment satisfaction is directly related to adherence [97]

PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats