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Careful adjudication of suspected cases was necessary to scrutinize details of the symptomatic presentation, the degree of elevation on pancreatic enzymes, and the diagnostic specificity of imaging data (68)

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Cutcliffe recalls "getting rejected up and down Silicon Valley" , but she persevered, and with seed capital from the Mayo Clinic, Pendulum was able to engineer its own oxygen-free fermentation process to manufacture Akkermansia as well as other proprietary strains

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