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Its been consistent, real results. Average weight loss in 1 year is 11-20% (vs ~2-3% with diet and exercise alone)
Despite the overall growth in the diabetes market, sales of Byetta steadily declined to $254 million (5.1% market share) in 2016 and $176 (2.7% market share) in 2017 (Figure 7, Table 5) due to competition from other safer and more convenient GLP-1 RAs

If you have fatigue, cold sensitivity, constipation, dry skin or unexplained weight gain, your provider may recommend thyroid testing

From a pharmacological perspective, tirzepatide acts primarily through GIP and GLP-1 receptor pathways to modulate insulin secretion, glucagon suppression, and appetite regulation

[1] [2] The mechanism of action involves activating both GIP and GLP-1 receptors, which reduces appetite, slows gastric emptying, and improves glycemic control
