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Amputation The CANVAS Program raised a concern regarding an association between canagliflozin and minor and major amputations
La chetoacidosi diabetica stata segnalata in pazienti insulino-dipendenti che hanno avuto una rapida interruzione o riduzione della dose di insulina quando iniziato il trattamento con unagonista del recettore del GLP-1 (vedere paragrafo 4.2)
Three patients (27%) developed low complement and/or anti-dsDNA antibodies at 6-10 months
However, Long-term weight maintenance represents one of the biggest challenges in obesity treatment
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