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Rahn, S., Zimmermann, V., Viol, F., Knaack, H., Stemmer, K., Peters, L., Lenk, L., Ungefroren, H., Saur, D., Schfer, H., et al

This means that patients taking levothyroxine for hypothyroidism or other thyroid medications can typically use semaglutide without loss of thyroid treatment benefit, provided proper dosing timing and monitoring are maintained

However, patients experiencing significant weight loss on GLP-1 therapy may require more frequent monitoring, with TSH rechecked 6-8 weeks after significant weight change or dose adjustment, then every 3-4 months during active weight loss

[DOI] [PubMed] [Google Scholar] Astorino TA, Schubert MM (2018) Changes in fat oxidation in response to various regimes of high intensity interval training (HIIT)

This is one of the most anticipated readouts, as it will provide the broadest picture of retatrutide's weight loss efficacy in a general obesity population
