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Emphasizing the value of these incretin-based options for better understanding treatment mechanisms, she said she hopes additional options will emerge to offer benefits beyond weight loss and diabetes management, including disease-modifying effects

Fat in our face helps to give us a more youthful look Facial muscle loss: Each side of our face contains around 30 muscles that control our facial expressions and enable us to chew and swallow and perform other functions, such as blinking and yawning

Vomiting also reduces the amount of fluid in the body

Cevimeline is another prescription sialagogue that works through a similar mechanism but with potentially fewer cardiovascular side effects than pilocarpine

A subsequent analysis of SELECT trial data presented at the 2025 European Congress on Obesity found that the heart benefits appeared within just a few weeks of starting the medication and were not entirely explained by weight loss alone