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2025;26:e13841

In the tirzepatide vs retatrutide comparison, tirzepatide activates the GIP and GLP-1 receptors, while retatrutide adds the glucagon receptor (GCGR)

Regular check-ins via telehealth can also help reinforce adherence to treatment plans, ensuring that patients remain on track while managing their fatigue effectively

Every patient begins with a comprehensive evaluation to assess metabolic function, medical history, and personal goals
