retatrutide clinical trial retatrutide drug The results of the are comparable to what is seen with bariatric surgery, according to Eli Lilly Retatrutide: What We Know About

Muscle loss While most weight loss includes some level of muscle loss, research shows that the percentage can be much higher in people taking GLP-1s amounting to 15%40% of their total weight loss

Week 1: Early Appetite Changes During the first week, your body begins adjusting to treatment

Mounjaro (tirzepatide) uniquely targets both GLP-1 and GIP receptors, potentially offering more substantial weight reduction and improved glycemic control compared to other GLP-1RAs that only target the GLP-1 receptor, such as Ozempic (semaglutide)

Clinical uses Type 2 Diabetes Mellitus (T2DM) : Effective in lowering blood glucose without a significant risk of hypoglycemia

The region benefits from strong GLP-1 penetration in the United States, where prescriptions exceeded 7% of all dispensed prescriptions by December 2025