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Even though some individuals with excess adiposity might be relatively metabolically healthy compared to others with a similar BMI, they may still be considered at risk for obesity-related primarily non-metabolic complications (e.g., osteoarthritis, gallstones, gastro-oesophageal reflux disease) 3

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There is no absolute contraindication to consuming alcohol while taking tirzepatide (Mounjaro, Zepbound), and the FDA-approved prescribing information does not list alcohol as a formal drug interaction