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These adverse reactions can range from mild to severe, and in some cases, life-threatening complications have occurred
Grading of the results The Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology was used to assess the quality of evidence for each outcome in the meta-analysis [24]
Semaglutide should not be used in patients or subjects with a personal or family history of medullary thyroid carcinoma (a type of thyroid cancer) or in those with multiple endocrine neoplasia syndrome type 2 (a genetic disorder associated with thyroid cancer) [16]
