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Management strategies that keep you on track Slow your titration: Extending each dose level from 4 to 68 weeks before escalating gives the GI tract more adaptation time

Analogous to Figure 2A, decreasing the dose frequency does not commensurately decrease weight loss efficacy

GLP-1 infusion slows gastric emptying of solid and liquid components of food and alters the distribution of food in the stomach so that a greater proportion of food is retained in the distal stomach (Marathe et al., 2011)

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These include how fast you lose weight, changes in diet, and how you personally react to the drug