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Gastroenterol Res Pract

Just make sure to include all of these factors in your decision

Empagliflozin had no clinically relevant effect on the pharmacokinetics of metformin, glimepiride, pioglitazone, sitagliptin, linagliptin, warfarin, digoxin, ramipril, simvastatin, hydrochlorothiazide, torsemide, and oral contraceptives when coadministered in healthy volunteers (see Figure 2)

So, uh, the, you know, these are prescription in the us there's other countries where you can get them yourselves, but you really wanna do this under a practitioner supervision

Cardiovascular side effects with semaglutide are generally mild, and the SELECT trial demonstrated a 20% reduction in major adverse cardiovascular events (MACE) in people with established heart disease