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Zooming out, the obesity market is now clearly split across modalities: Novo Nordisk still anchors the peptide side with semaglutide, while oral small molecules are accelerating (orforglipron, elecoglipron and Roches Carmot deal)

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The dynamics of this first wave of offpatent entrants will be shaped not just by the cost of development, but also by regulatory classification, privatemarket affordability, and innovators ability to segment the market with second brands and nextgeneration therapies

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