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Agents such as dulaglutide, liraglutide, semaglutide, and tirzepatide differ in pharmacology and dosing, directly influencing perioperative safety, particularly due to their effects on gastric motility and the high frequency of gastrointestinal (GI) adverse events that raise concerns about aspiration and postoperative morbidity in urgent or elective procedures

For Employers and PBMs: No Automatic Change, But Significant Leverage For employers, this announcement does not automatically lower GLP-1 costsPBM contracts remain as written

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