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Using them for short bursts without a plan for sustained support may lead to short-lived results, potential weight cycling and an unhealthy relationship with your body image. Plus, as Fitch points out, obesity is not about people learning to behavein this case, facilitating an appetite reset. Obesity is a complex chronic condition and taking something short term to learn to behave better is stigmatizing and places blame on patients, she explains

Short answer Zoloft and GLP-1 medications may be used together under physician supervision

DPP-4 (Dipeptidyl Peptidase-4) DPP-4 is an enzyme that breaks down GLP-1 and GIP, which can reduce their effectiveness: Lowers GLP-1 and GIP Levels: DPP-4 can make it harder for your body to control blood sugar and hunger by breaking down these hormones