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GLP-1 is released from L cells, which are mainly located at the ileum, the distal part of the gastrointestinal tract, and is triggered by neuronal or hormonal stimulation and direct nutritional components, including carbohydrates, amino acids, proteins, and fatty acids [15,16,17,18]

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The absence from this map worth noting is Roche, whose publicly disclosed obesity strategy is concentrated on dual GLP-1/GIP (CT-388) and does not include a triple-agonist deal or disclosed internal program

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