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Therefore, it remains unclear whether the impacts of GLP-1RAs and SGLT-2is on gut microbiota are additive, redundant, or interactive

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Obesity is the major risk factor for OSA, primarily due to the deposition of adipose tissue in the pharyngeal walls, tongue, and abdominal cavity, which increases upper airway collapsibility and reduces lung volume during sleep, predisposing individuals to airway obstruction [11, 12]

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If you've been waiting for a reason to revisit the question, the November 2025 FDA announcement is it

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