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Although reported AEs are generally not serious and safety and efficacy in older adults are generally comparable to those in younger adults [36], higher AE rates may nonetheless predispose older adults to additional risks that are more critical in this population, such as hypoglycemia, dehydration, or impaired renal function

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The research fueling these claims includes studies that found semaglutide users may face a significantly higher risk of developing NAION compared to patients using other medications