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Roberta Lost 32 lbs I was feeling overwhelmed and anxious all the time for being overweight
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Ross, Mindy M

The typical dose escalation for semaglutide dosing follows this pattern: Each dose increase can trigger a fresh wave of bloating that typically peaks 3 to 5 days after the increase and then gradually subsides over the following 1 to 2 weeks

A 2025 study published in JAMA Network Open found that most patients with obesity discontinue GLP-1 therapy within a year, particularly those without type 2 diabetes 1
