retatrutide phase 2 trial obesity nejm 2023 triple agonist 🚨 BREAKING: Shows “Bariatric-Level” Weight Loss in 3 New Phase 3 TRIUMPH-1 data show retatrutide may deliver weight-loss outcomes approaching those seen with bariatric surgery—marking one of the most Another Promising Medication (Retatrutide) for
Description
This suggests the true ceiling for Tirzepatide may be slightly higher than what SURMOUNT-1 captured

How does tirzepatide help with weight management

Semaglutide : Weight loss includes both fat and lean mass reduction, typical of GLP-1 agonists
Introduction The biological effects of the Glucagon-like peptide-1 (GLP-1) are mediated by binding to its receptor, GLP-1R, a specific seven-transmembrane receptor guanine nucleotide-binding protein (G-protein) coupled receptor (GPCR) (1)

Overall, integrating GLP-1 RAs into the management of mood disorders represents a biologically sound and clinically promising strategy
