glp -1 side effects Ozempic and GLP-1 Drugs: Risk of Severe What is GLP-1? Benefits, Uses
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10.1016/s0140-6736(19)31271-1 64 RamracheyaR.ChapmanC.ChibalinaM.DouH.MirandaC.GonzlezA.et al (2018)

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Abnormalities in the structure and function of the autonomic nervous system and smooth muscles play an active part in the pathogenesis

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The two scientists overcame the problem by engineering fatty acids that bound more strongly to albumin so that it would stick longer to GLP which would make it remain active for longer in the body