ecnoglutide vs tirzepatide For the first time, and semaglutide were put in the same trial. SURMOUNT-5. Phase 3b RCT. 751 adults with obesity, no diabetes. 72 weeks. Both drugs at maximum tolerated dose. The GLP-1 Receptor Agonists | New
Description
Efficacy signal: Trial data shows tirzepatide achieves 20.9% average weight loss (SURMOUNT-1) versus semaglutide's 14.9% (STEP 1), but individual outcomes vary and no obesity-specific switching trial exists yet

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