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These fibres are fermented by beneficial bacteria into short-chain fatty acids such as butyrate and propionate, which activate receptors on intestinal L-cells responsible for GLP-1 secretion

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Studies suggest GLP-1 drugs like Semaglutide and Tirzepatide may help reduce cravings for alcohol, opioids, and nicotine

Retatrutide side effects are mostly mild gastrointestinal issues during dose escalation

Migraines occur in some GLP-1 users, but mechanisms remain incompletely understood