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Edfalk S, Steneberg P, and Edlund H

Inflammatory mediators can cross the bloodbrain barrier, activating the microglia and leading to the release of neurotoxic factors with adverse effects on dopaminergic neurons [21]

1% achieving 20% WL respectively (Table 1) [45]

This integration exemplifies process analytical technology (PAT) and quality by design (QbD) principles, preventing batch deviations and ensuring consistent product quality from the outset [499, 500]
