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The medication does the heavy lifting

But that biology has a long and uncertain gestation

[54] in women with PCOS, BMI 25 kg/m 2 and/or insulin resistance, treatment with liraglutide 1.8 mg/day for 26 weeks, along with a higher weight loss, induced significant reductions in fasting plasma glucose, HbA1c, and plasma glucose AUC, whereas Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), Matsuda index and insulin AUC remained unchanged

Its not just extra pounds, but also where that fat is stored that changes in perimenopause (the years before your period stops) and menopause

Hyperglycemia induces NF-kappaB activation and MCP-1 expression via downregulating GLP-1R expression in rat mesangial cells: inhibition by metformin