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No randomized controlled trials have enrolled breastfeeding women taking semaglutide, so direct evidence of infant exposure or outcomes is absent

Injection site discomfort: Minimal

Targeting 0.7-1.0 grams of protein per pound of goal body weight helps preserve lean mass

This article lays out the common reasons: dose and timing, appetite suppression, calories, insulin resistance, thyroid issues, water retention, medication interactions, sleep, and stress