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Furthermore, the dissociation rate with the receptor is slow, and the high affinity and slow dissociation with the receptor prolongs the time of pharmacological effect (58, 60)

Preclinical data from SureNano Science suggest that GEP-44 may offer substantive differentiation relative to earlier-generation GLP therapies

Research in recent years has focused on GLP-1RAs stimulating the therapeutic target of GLP-1R [96]
Improved glycemic control and reduced blood sugar levels are achieved without increasing the risk of hypoglycemia low blood sugar a common concern with other diabetes medications

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