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In addition to established efficacy for glycaemic control and weight loss, there has been growing enthusiasm surrounding the cardioprotective effects of GLP-1 agonists, as demonstrated from their superiority to placebo in multiple large studies in preventing major cardiovascular adverse events, namely reduced rates of myocardial infarcts, stroke, and rates of revascularisation procedures (Table 2)
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The current wave of healthcare innovation such as artificial intelligence (AI)-powered drug discovery coupled with GLP-1s could raise the level of US GDP by 1.3% in the coming years, equivalent to $360bn per year in current exchange rates, with potential for an increase ranging from 0.6% to 3.2%
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Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review
