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Description
Orals: Metsera candidates + YP05002 Two distinct oral GLP-1 families now in development some overlap risk, but Pfizer can segment by tolerability, dosing, and combination potential

Research Applications in Metabolic Disorders GLP-1 analogs are widely investigated for effects on type 2 diabetes, obesity, and cardiovascular health in laboratory settings

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Farnesoid X receptor (FXR) interacts with CREB to inhibit intestinal L cell secretion of GLP-1 [178]

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