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Extreme sensitivity reactions such as rash, trouble breathing, swelling of the mouth, face, or throat should be reported to your pharmacist and physician

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Subjects were excluded if they had clinically significant concomitant diseases or disorders, clinically significant abnormal values in laboratory screening tests, any history of gastrointestinal surgery (except uncomplicated surgical procedures such as appendectomy and hernia surgery), or if they smoked more than five cigarettes or the equivalent per day

How does this compare to just using a higher dose of retatrutide