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In CNS, GIP-R is expressed on the surface of cells both alone and in association with GLP1-R (60), acting on the same cells (facilitating GLP-1 internalization to specific neuronal populations (61)) or, as documented in other studies, on different cells (62)

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Some people may respond well at 5 mg, while others may need a higher dose to reach their goals

On average, participants lost between 10% and 30% of their initial weight

Patients should be informed about the importance of adherence, recognizing symptoms of hypoglycemia, and managing common side effects like nausea and diarrhea