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The majority of patients died within the first month after delivery and major causes of death were heart failure, sudden cardiac death and pulmonary embolism 4,5,8 Complications of PH during pregnancy: The normal physiologic changes of pregnancy (increased plasma volume, increased stroke volume, increased cardiac output, decreased systemic vascular resistance), are poorly tolerated in PH due to an inability to decrease pulmonary vascular resistance and accommodate the increased pulmonary flow

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At week 32, the mean reduction in AHI with liraglutide was statistically significant compared with the placebo (estimated treatment difference: 6.1 events h 1 (95% CI, 11.0 to 1.2)

Semaglutide itself lowers blood glucose levels, so adding other glucose-lowering drugs without dose adjustments can cause hypoglycemia