is glp 1 the same as zepbound a GLP-1? Zepbound leads to more weight

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(Lond.) 34, 13411344

Orskov C, Bersani M, Johnsen AH, Hojrup P, and Holst JJ

Furthermore, through the extracellular-signal-regulated kinase 5 (ERK5) pathway, GLP-1 RAs have been shown to increase Krppel-like factor 2 (KLF2) levels and prevent inhibition of mitogen-activated protein kinase (MAPK), which causes downstream anti-inflammatory effects, including decreased leukocyte adhesion [132]

The FFA-induced rise in intracellular Ca 2+ is substantially reduced when cells are cultured in a Ca 2+ free medium, and is abolished upon treatment of cells with the Ca 2+ channel inhibitor nicardipine [292] or when using BSA (which binds fatty acids) [251]