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And then there is the question of loyalty: Read that last one again

is supported by the American Heart AssociationBristol Myers Squibb Foundation through the Winn Diversity in Clinical Trials Clinical Investigator Leadership Award, and by the National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Physician-Scientist Career Development Award, Grant Number K12DK133995 (David Maahs, Linda DiMeglio, Multi-Center Program Directors)

Wing et al., 2011)

Weight loss yields reductions in total, visceral and pancreatic adipose tissue, reductions in intrahepatic levels of lipids, and improved insulin sensitivity, all of which are expected to improve systemic glucose metabolism 18

Dose-dependent effects were consistently observed, with greater doses correlating to higher efficacy