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Second, magnesium has a modest effect on blood pressure and may potentiate the effects of antihypertensive medications

In terms of glycemic control, these agents affect glucose metabolism through distinct pathways: GLP-1RAs enhance glycemic control by stimulating glucose-dependent insulin secretion, while SGLT2is lower blood glucose levels by inhibiting glucose reabsorption in the proximal renal tubules, leading to increased urinary glucose excretion

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Dulaglutide and lixisenatide continue to be key molecules in terms of importance for the time being, however, as the pipeline molecules can offer a wide variety of innovative formulations the competition is growing

121:416-422 [PubMed: 8053615] 415
