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GLP-1 Receptors Exist Throughout the Body Although GLP-1 medications work in the pancreas to regulate insulin and glucagon, GLP-1 receptors are widely distributed in other areas of the body, including the brain, cardiovascular system, immune system, gut, and kidneys, says Diana Isaacs, PharmD, CDCES, an endocrine clinical pharmacy specialist in the Endocrine and Metabolism Institute at Cleveland Clinic in Ohio

Abusing Vyvanse can also cause heart arrhythmia and psychosis, according to Dr

They have these physiological effects together with other neuropeptides, such as neuropeptide Y (NPY), opioid peptides, galanin, vasopressin, and GHRH

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