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Finally, beyond their role in controlling metabolic processes, GLP-1 receptor agonists also show promising potential benefits in treating cardiovascular and neurodegenerative diseases

A cardiac magnetic resonance substudy of the SUMMIT trial showed that tirzepatide treatment led to a placebo-corrected reduction of left ventricular mass by 11 g ([95% CI 419 g]

Mean body-weight reduction reached 22.5% with the 15 mg dose, compared with 2.4% with placebo

Energy levels may dip initially