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Germany dominated the market in Europe owing to the presence of many endocrinology and obesity specialists, a healthcare insurance system that covers GLP-1 drugs, and the presence of the pharmaceutical industry that has adopted these drugs for diabetes as well as obesity

FIGURE 3 To further elucidate the association between GLP-1 RAs and DPP-4 inhibitors with biliary disorders, we analyzed data across various gender and age groups (Figure 4)

Hayashi N, Iida T, Yamada T, Okuma K, Takehara I, Yamamoto T, et al

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Side note: I say earlier because research shows that many people with symptomatic osteoarthritis follow a delayed-response trajectory, where meaningful improvements dont appear until the 812 week mark