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Electrolyte monitoring is not routinely required for all GLP-1 users, but becomes essential when patients experience persistent gastrointestinal symptoms or have additional risk factors such as chronic kidney disease, heart failure, age over 65, or concurrent diuretic use

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The FDA states that available data is insufficient to evaluate for a drug-associated risk of major birth defects, miscarriage, or other maternal or fetal outcomes. What we do have comes primarily from animal studies, and those findings raised concerns