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Additional studies will be required to determine whether metformin can increase incretin receptor expression in human beta cells and thereby bolster incretin action in a meaningful way

Higher doses of oral semaglutide (up to 50 mg/day) are under development for the treatment of both T2DM (104) and obesity (105), with effectiveness on par with 2.4 mg/week subcutaneous semaglutide approved for weight management

Myth: Taking it early makes it work faster False

It is also used to treat narcolepsy in children 12 and older and adults