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Figure 1 Until now the specific etiological mechanism of hypertension has not yet been fully identified, and choosing the most appropriate and effective antihypertensive drugs is still a problem
This can result in a reduced need for thyroid hormone replacement, particularly in patients who initially required higher doses due to obesity-related factors like increased inflammation or altered hormone metabolism

Furthermore, noted that GLP-1RAs can increase cholesterol excretion and reduce cholesterol accumulation by promoting the expression of ATP-binding cassette transporter A1 (ABCA1) in the endothelium

Facial changes become obvious during this phase

Conventionally, the selective vulnerability of neuronal populations to disease processes is usually attributed to their inherent properties (i.e., high metabolic rate, ROS generation, and extensive arborisation with increased energy demand) [133,136,137]
