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Last reviewed: May 16, 2026 Last updated: May 16, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

When patients increase from 0.25 mg to 0.5 mg weekly (or equivalent oral doses), the GI tract is exposed to stronger receptor activation

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However, its impact extends beyond glucose metabolism and includes effects on gastrointestinal physiology and possibly the immune response