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In addition, insulin profoundly affects lipid metabolism by increasing lipid synthesis in liver and fat cells (Fig

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Additionally, somatostatin inhibits gastrointestinal activity, reducing pancreatic enzyme and gastric acid secretion, which indirectly decreases glucagon demand

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Inhibition of ENaC by serin protease inhibitors has been shown to reduce profibrotic markers, while high salt diet activates fibroblasts 31

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