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In renal failure, the dose of the sulfonylurea agent will require adjustment based on glucose monitoring to avoid hypoglycemia (20)

Diabetic retinopathy is a prognostic factor for progression of chronic kidney disease in the patients with type 2 diabetes mellitus

Intestinal barrier dysfunction as a therapeutic target for cardiovascular disease

In addition, NPY2R (Nguyen et al., 2011) is expressed mainly in the human ileum, colon, pancreatic gland, and prostate regions, whereas NPY4R (Lin et al., 2009) and NPY5R (Reichmann et al., 2016) are mainly expressed in brain tissue

A clinician also needs to consider pregnancy plans, gallbladder concerns, pancreatitis history, digestive conditions, diabetes medications, and other individual factors