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Comparing clinical trial population representativeness to real-world populations: an external validity analysis encompassing 43 895 trials and 5 685 738 individuals across 989 unique drugs and 286 conditions in England. The Lancet Healthy Longevity 3.10 (2022): e674-e689

[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Mahato RI, Narang AS, Thoma L, Miller DD

After a big dinner with spicy and greasy food, a person may get sleepy

median survival, 11.0 months vs

Lithium's exact mechanism of action (MOA) is unknown, but the drug is believed to exert its mood-stabilizing effects by interfering with the synthesis, storage, release, and reuptake of monoamine neurotransmitters