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However, as demonstrated in that same report, concomitant administration of exendin9-39 and a DPP-4 inhibitor increased food intake by 20%, suggesting that GLP-1, when potentially acting in concert with other gut hormones, might have an important role in the metabolic benefits achieved by bariatric surgery [224]

NICE guidance recommends regular monitoring of glycaemic control and tolerability for patients on GLP-1 receptor agonists, but not routine cortisol assessment

Possible candidates include substances that modulate various subtypes of NMDA glutamate receptors or gamma-aminobutyric acid (GABA) receptors

If you're at 5 mg weekly, your half-dose is 25 units (at 10 mg/mL)

Only a small minority, fewer than 10%, say usage of GLP-1s is viewed positively