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GLP-1 receptor agonist exerts its action through the GLP-1R

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This fatigue results from how GLP-1 affects the bodys metabolism, appetite, and energy regulation

Diabetes Care 32:14211424 Nieuwdorp M, Stroes ES, Kastelein JJ (2007) Normalization of metabolic syndrome using fenofibrate, metformin or their combination

This trend is further corroborated by another study, which, using claims data, observed a notable increase in the first-line use of GLP-1RAs from 6% to 18% from January 2022 to May 2023