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The combination of strong GLP-1 appetite suppression with meaningful GIP-mediated metabolic improvement creates a synergistic effect that exceeds what either receptor could produce alone, a principle similar to why peptide stacking sometimes outperforms individual compounds

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The term Ozempic teeth has become a way to describe the dental side effects some patients report while using semaglutide or other GLP-1 medications

2) Steroid hypercholesterolemia Corticosteroids worsen lipid profiles (including increased low-density lipoprotein cholesterol and triglycerides), contributing to plaque formation and faster vascular remodeling