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GLP-1 RAs have pleiotropic actions, with intervention on multiple regulation mechanisms

This article explores the potential of GLP-1 agonists in treating MASH, examining their mechanisms of action, clinical benefits, and the challenges associated with their development as a liver disease treatment

The exclusive expression of GCG in pancreatic -cells, enteroendocrine L cells, and some neurons in the brainstem underlines its pivotal role (57)

23 The assessment of major birth defects was restricted to live births and pregnancy losses with confirmed outcomes after appropriate medical examination, ensuring reliable knowledge of birth defect status

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