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Many patients experience improvement in gastrointestinal symptoms within several weeks as tolerance develops, though individual experiences vary

These medications are primarily used for managing type 2 diabetes and can also be used for weight management in individuals who are overweight or obese

Gastrointestinal side effects like constipation occur in approximately one-quarter of patients beginning GLP-1 receptor agonist therapy, often appearing within the first two weeks of treatment

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When combined with the loss of lean muscle, which burns calories faster than fat, this slow-down can promptly result in weight gain even if diet and exercise habits remain constant